Drug Standards
Apexbio Technology LLC Cladribine 4291-63-8 10mM (in 1mL DMSO)
Cladribine (CAS 4291-63-8) is a purine nucleoside analog functioning as an inhibitor of adenosine deaminase an enzyme critical in purine metabolism It demonstrates potent antiproliferative effects on lymphoproliferative diseases notably hairy cell leukemia In multiple myeloma cell lines (U266 RPMI8226 MM1 S) Cladribine inhibits cell proliferation and induces apoptosis in a dose-dependent manner associated with activation of caspase pathways (caspase-3 -8 -9) and PARP cleavage inhibition of STAT3 phosphorylation DNA damage and activation of tumor suppressor p53 Cladribine is widely investigated for oncology research applications due to these molecular mechanisms
Apexbio Technology LLC Benzylpenicillin potassium 113-98-4 250mg
Benzylpenicillin potassium (113-98-4) is a beta-lactam antibiotic targeting penicillin-binding proteins (PBPs) It is designed to inhibit bacterial cell wall biosynthesis by interfering with peptidoglycan cross-linking thereby reducing bacterial stability and inducing cell lysis Benzylpenicillin potassium exerts its biological activity primarily through inhibition of PBPs To date specific IC50 concentrations of Benzylpenicillin potassium vary according to bacterial strains experimental conditions and assay methodologies employed in antimicrobial susceptibility studies Based on these pharmacological properties Benzylpenicillin potassium holds research potential in investigating bacterial infections associated with blood cardiac tissue pulmonary structures joints and reproductive organs
Sigma Aldrich Fine Chemicals Biosciences Acarbose United States Pharmacopeia (USP) Reference Standard | 56180-94-0 | MFCD00869592 | 200MG
Acarbose United States Pharmacopeia (USP) Reference Standard | Mol Wt: 645.6 | 56180-94-0 | MFCD00869592 | 200MG
Sigma Aldrich Fine Chemicals Biosciences Duloxetine Related Compound H United States Pharmacopeia (USP) Reference Standard | 199191-66-7 | 30MG
Duloxetine Related Compound H United States Pharmacopeia (USP) Reference Standard | Mol Wt: 397.49 | 199191-66-7 | 30MG
Sigma Aldrich Fine Chemicals Biosciences Racecadotril impurity G European Pharmacopoeia (EP) Reference Standard | 81110-69-2 |
Racecadotril impurity G European Pharmacopoeia (EP) Reference Standard | Mol Wt: 343.44 | 81110-69-2 |
Apexbio Technology LLC Alverine Citrate 5560-59-8 10mM (in 1mL DMSO)
Alverine citrate (CAS 5560-59-8) is a synthetic small-molecule compound employed primarily in studies of functional gastrointestinal disorders It exerts antispasmodic effects predominantly via calcium channel blockade reducing smooth muscle contraction and alleviating gastrointestinal symptoms Biomedical researchers utilize alverine citrate to examine gut motility mechanisms visceral hypersensitivity pathways and potential therapeutic approaches for gastrointestinal dysfunction
Sigma Aldrich Fine Chemicals Biosciences Lactulose European Pharmacopoeia (EP) Reference Standard | 4618-18-2 | MFCD00151469 |
Lactulose European Pharmacopoeia (EP) Reference Standard | Mol Wt: 342.3 | 4618-18-2 | MFCD00151469 |
Sigma Aldrich Fine Chemicals Biosciences Fenoprofen sodium United States Pharmacopeia (USP) Reference Standard | 66424-46-2 | 500MG
Fenoprofen sodium United States Pharmacopeia (USP) Reference Standard | Mol Wt: 300.28 | 66424-46-2 | 500MG
Cayman Chemical ChlorambucIl-d8 1mg
An internal standard for the quantification of chlorambucil by GC- or LC-MS
Apexbio Technology LLC Benazepril HCl 86541-74-4 250mg
Benazepril hydrochloride (CAS 86541-74-4) is a small molecule inhibitor targeting angiotensin converting enzyme (ACE) a key protease involved in converting angiotensin I to the bioactive vasoconstrictor angiotensin II By suppressing ACE activity benazepril HCl reduces angiotensin II-mediated vasoconstriction and aldosterone secretion leading to vascular relaxation and decreased blood pressure In biomedical research benazepril hydrochloride serves as a useful tool for investigating pathways involved in hypertension cardiovascular disorders and angiotensin signaling regulation
Selleck Chemical LLC BAY 87-2243 10mg 1227158-85-1
BAY 87-2243 is a potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor. BAY 87-2243 inhibits mitochondrial complex I activity, thus triggering a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis. BAY 87-2243 exerts antitumor activity. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Oxymatrine 100mg 16837-52-8 Matrine N-oxide
Oxymatrine (Matrine N-oxide) is a quinolizidine alkaloid extracted from the root of Sophora flavescens with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-?/Smad pathway. It is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
![eMolecules Medchem Express / KPT-6566 / 1mg / 489863088 / HY-123847 / / 881487-77-0 / [null] / 443.530 / C22H21NO5S2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502460789.JPG-250.jpg)
eMolecules Medchem Express / KPT-6566 / 1mg / 489863088 / HY-123847 / / 881487-77-0 / [null] / 443.530 / C22H21NO5S2
Medchem Express / KPT-6566 / 1mg / 489863088 / HY-123847 / / 881487-77-0 / [null] / 443.530 / C22H21NO5S2
MOLTOX Molecular Toxicology Inc Cyclophosphamide, 1 mg/vial, 5 vials/pack, Store in Refrigerator
For use in Ames test with TA1535 & TA100 tester strains. Dose 100 µg/plate. Reconstitute in organic solvent such as DMSO or sterile dH2O as applicable. Indirect acting mutagens require the use of S9 metabolic activation to cause mutagenicity. CONTROLCHEM™ chemicals are obtained from major suppliers of research chemicals and are employed without further characterization or purification. Packaged quantities are precise within 1%. Please Note: CONTROLCHEM™ chemicals are known mutagens/carcinogens/toxins and are sold only to those experienced in the safe handling and disposal of hazardous materials. Consult your Institutional Safety Officer before ordering.
Medchemexpress LLC Etoricoxib impurity 2 | 349536-41-0 | MFCD31536313 | 25mg
Etoricoxib impurity 2 is an impurity of Etoricoxib (HY-15321)